Frequency of hypotension in lumbar spinal anesthesia with prophylactic use of fluid Gelofusine versus Synephrine in women undergoing cesarean section

Abstract

Objectives:to assess the frequency of hypotension in women undergoing cesarean section under lumbar spinal anesthesia, with prophylactic administration of either fluid Gelofusine or Synephrine.

Methodology: A randomized controlled trial was conducted at the Department of Anesthesiology, Nishtar Hospital Multan, from April 29th, 2019, to October 28th, 2019. The trial consisted of 120 participants, with 60 individuals allocated to each group.Patients were randomly assigned to either group A (prophylactic fluid preload) or group B (vasopressor) using sealed envelopes.

Results: The mean ages were 28.38 ± 5.90 years for group A and 28.97 ± 6.01 years for group B. Frequency of hypotension observed was 51.67% with use of fluid Gelofusine and 70.0% with Synephrine, as outlined in Table 2, with a statistically significant p-value of 0.040.

Conclusion: Gelofusine preload during the induction of spinal anesthesia for elective cesarean section demonstrates a lower frequency of hypotension compared to synephrine preload, suggesting its routine utilization in our general practice to prevent spinal-induced hypotension and effectively manage patients undergoing spinal anesthesia.